Bradykinin Mediated Angioedema

Authors

  • Chrystyna Kalicinsky, MD

DOI:

https://doi.org/10.58931/cait.2021.1110

Abstract

A 36-year-old female is referred with recurrent angioedema without urticaria, unresponsive to antihistamines, corticosteroids, and epinephrine. Her episodes can last for more than 3 days. Bradykinin angioedema can affect mucous membranes of the oropharynx, as well as the larynx, subcutaneous tissue, bowel mucosa, and the abdominal wall. Angioedema without urticaria, which is unresponsive to antihistamines, corticosteroids and epinephrine, is presumed to be caused by episodic buildup of bradykinin. This article will examine the medications known to be associated with bradykinin angioedema and provide an overview on hereditary angioedema (HAE), acquired angioedema (AAE) and idiopathic bradykinin mediated angioedema.

Author Biography

Chrystyna Kalicinsky, MD

Dr. Chrystyna Kalicinsky received her medical degree, as well as specialty training in internal medicine and clinical immunology and allergy from the University of Manitoba. From 2000–2005 she was in community practice. From 2005 onwards, she has been in academic practice at the University of Manitoba where she was the Program Director of the Clinical Immunology and Allergy Training Program at the University of Manitoba from 2009 until 2020. Dr. Kalicinsky enjoys teaching medical students and residents, as well as patient education and her clinical interests include immunodeficiency, angioedema, chronic urticaria and mast cell disorders.

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Bradykinin Mediated Angioedema

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Published

2021-03-01

How to Cite

1.
Kalicinsky C. Bradykinin Mediated Angioedema. Can Allergy Immunol Today [Internet]. 2021 Mar. 1 [cited 2024 Dec. 4];1(1):13–18. Available from: https://canadianallergyandimmunologytoday.com/article/view/1-1-kalicinsky

Issue

Volume 1, Issue 1, March 2021

Section

Articles