Component-Driven Oral Food Challenges in the Community

Authors

  • Julie Wang, MD
  • Shouling Zhang, MD

DOI:

https://doi.org/10.58931/cait.2022.2127

Abstract

The diagnosis of immunoglobulin E (IgE) mediated food allergy is based on the clinical evaluation of a patient’s history, physical examination, and specific test results.These tests may include skin prick testing, serum IgE testing, and/or oral food challenge (OFC). Component-resolved diagnosis (CRD) targeting specific allergenic proteins in a food has the potential for improved diagnostic accuracy compared to serum IgE testing to whole allergens. An overview of the clinical considerations of how and when to proceed with an OFC will be outlined in this review, with special consideration given to the utility of component testing in making this determination.

Author Biographies

Julie Wang, MD

Dr. Julie Wang is Professor of Pediatrics in the Division of Allergy and Immunology at the Icahn School of Medicine at Mount Sinai. Her research focuses on clinical trials investigating novel food allergy therapies, food allergy management, and anaphylaxis in schools. She serves on the Joint Task Force on Practice Parameters, is Chair of the Executive Committee, Section on Allergy and Immunology of the AAP, and serves on the Editorial Board of the Journal of Allergy and Immunology and Journal of Allergy and Immunology: In Practice. She is co-program director for the Mount Sinai Allergy and Immunology Fellowship Training Program.

Shouling Zhang, MD

Dr. Shouling Zhang is currently a second year clinical fellow in allergy and immunology at Icahn School of Medicine at Mount Sinai. She graduated from University of Rochester with a dual degree in Biological Sciences: Microbiology and Psychology. She went on to receive her medical degree at Stony Brook University School of Medicine and completed her residency training in pediatrics at Cohen Children’s Medical Center in New York. Her interests include clinical research and practice, with a special interest in food allergy and childhood atopy.

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Component Driven Oral Food Challenges in the Community

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Published

2022-04-01

How to Cite

1.
Wang J, Zhang S. Component-Driven Oral Food Challenges in the Community. Can Allergy Immunol Today [Internet]. 2022 Apr. 1 [cited 2025 Jan. 15];2(1):9–14. Available from: https://canadianallergyandimmunologytoday.com/article/view/2-1-wang-zhang

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Volume 2, Issue 1, April 2022

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Articles