Hypereosinophilia: A Guideline for Workup in the Allergy Community

Authors

  • Joshua O’Connell, MBBS
  • Michael Trus, MD, PhD

DOI:

https://doi.org/10.58931/cait.2022.2232

Abstract

Determining the etiology of eosinophilia, defined as an absolute eosinophil count (AEC) greater than 500 cells/µL, is often difficult given the many potential causes spanning several medical specialties. The diagnosis becomes more urgent in the case of hypereosinophilia (≥1,500 cells/µL) due to concerns over potential end organ damage. The goal of this review is to educate physicians about the biology, etiologies, and workup of hypereosinophilia.

Author Biographies

Joshua O’Connell, MBBS

Dr. Joshua O’Connell is a clinic manager and physician assistant for a family practice in Toronto, Ontario. He received his medical degree from St. George’s University of London, England and completed a post-doctoral research fellowship with a focus on pediatric surgery and stem cell research at The Hospital for Sick Children in Toronto, Ontario.

Michael Trus, MD, PhD

Dr. Michael Trus received his MD degree from Dalhousie University and completed residencies in internal medicine and hematology in Ottawa, Ontario. He completed his PhD studies in the field of epigenetic regulation of acute myelogenous leukemia at the Princess Margaret Hospital in Toronto, Ontario. Dr. Trus currently works in Hamilton, Ontario where he specializes in the treatment of malignant hematological diseases and allogeneic stem cell transplantation. His practice also focuses on the treatment of patients with eosinophilic and mast cell disorders. Dr. Trus serves as the Co-Director of the Eosinophilic Lung Disorders clinic at St. Joseph’s Hospital, Hamilton, ON along with Dr. P. Nair.

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Published

2022-07-01

How to Cite

1.
O’Connell J, Trus M. Hypereosinophilia: A Guideline for Workup in the Allergy Community. Can Allergy Immunol Today [Internet]. 2022 Jul. 1 [cited 2024 Jul. 8];2(2):20–23. Available from: https://canadianallergyandimmunologytoday.com/article/view/2-2-oconnell_et_al

Issue

Volume 2, Issue 2, July 2022

Section

Articles