An Overview of Cannabis Allergy

Authors

  • Dennis Wong, MD, PhD
  • Gordon Sussman, MD, FRCPC, FAAAAI

DOI:

https://doi.org/10.58931/cait.2022.2234

Abstract

Cannabis refers to a genus of annual, herbaceous, dioecious flowering plants that are members of the family Cannabaceae, which include about 102 plant species.Although there is much debate, the most common taxonomy is that the genus Cannabis comprises one species, Cannabis sativa L (C. sativa)., which includes the highly polymorphic subspecies sativa, and indica. Hemp and cannabis both refer to the same species C. sativa; however, there is important distinction between the two. Whereas hemp (fiber-type) is grown for its cellulose-rich fiber in the stem, cannabis (drug-type) is cultivated for its flowers where the glandular trichomes produce the psychoactive delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD). THC provides the analgesic and relaxing effects of cannabis, whereas CBD produces other effects such as antiemetic and soporific properties. Researchers have used the THC content to define C. sativa subspecies sativa as containing less than 0.3% THC in dried flowering tops of female plants and C. sativa subspecies indicaas containing ≥0.3% THC.This threshold has been used by regulatory bodies to legally differentiate hemp plants (<0.3% THC) and cannabis plants (≥0.3% THC). Canada legalized the production, distribution, sale and non-medical use of cannabis for adults in October 2018. Recent data from nation-wide surveys show that approximately 6.2 million people aged 15 or older, or 20% in this age group, reported using cannabis in the past 3 months. which represents an increase from 14% before legalization. Cannabis can be used and/or ingested in a variety of forms including capsules, oils, dried flower, vaporization and through the consumption of edibles. With the increased use of recreational cannabis in Canada, it is expected that there will be a concomitant increase in cases of cannabis hypersensitivity.

Author Biographies

Dennis Wong, MD, PhD

Dr. Dennis Wong is a resident in Clinical Immunology and Allergy at University of Toronto. He completed his PhD in Microbiology and Immunology at University of British Columbia under the supervision of Dr. Yossef Av-Gay. He subsequently received his MD and completed Internal Medicine residency at University of Toronto.

Gordon Sussman, MD, FRCPC, FAAAAI

Dr. Gordon Sussman is a Professor of Medicine in the Division of Clinical Immunology and Allergy at University of Toronto. His research includes the characterization of marijuana allergy and allergens, which has become more relevant in recent years with its legalization and increased medicinal use. His previous research focused on natural rubber latex allergy. Dr. Sussman recognized and reported some of the first cases of latex allergy, which eventually lead to widespread declines in latex allergy.

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Published

2022-07-01

How to Cite

1.
Wong D, Sussman G. An Overview of Cannabis Allergy. Can Allergy Immunol Today [Internet]. 2022 Jul. 1 [cited 2024 Jul. 8];2(2):34–38. Available from: https://canadianallergyandimmunologytoday.com/article/view/2-2-wong_et_al

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