Hydrogen and methane breath testing for abdominal bloating of small intestinal origin

Authors

  • Jihong Chen, MD, PhD McMaster University, Department of Medicine, Division of Gastroenterology; Farncombe Family Digestive Health Research Institute, Hamilton, Ontario
  • Jan D. Huizinga, PhD McMaster University, Department of Medicine, Division of Gastroenterology; Farncombe Family Digestive Health Research Institute; School of Biomedical Engineering, Hamilton, Ontario

DOI:

https://doi.org/10.58931/cait.2023.3358

Abstract

Abdominal bloating with or without excessive gas production and with or without abdominal distention is common, very bothersome for patients, and is poorly understood. Bloating can be associated with gastrointestinal disorders, nutrient malabsorption, and systemic illnesses. The origin of abdominal bloating is often unclear, though it is usually associated with food intake and bowel motility dysfunction. Often, food allergies, food intolerance, or food poisoning are considered by the patient or physician as potential causes for bloating. A common concern in the patient’s mind is that healthcare professionals will dismiss or misdiagnose their complaint. The limited understanding of the pathophysiology of bloating leads to current empirical management, and bloating is often characterized as a “functional” disorder. Bloating carries a heavy clinical, psychological, and economic burden. Proper diagnosis will provide the patient with peace of mind and lead to effective treatment. This review focuses on the mechanisms and management of abdominal bloating associated with different small intestinal disorders identified by non-invasive hydrogen and methane breath tests.

Author Biographies

Jihong Chen, MD, PhD, McMaster University, Department of Medicine, Division of Gastroenterology; Farncombe Family Digestive Health Research Institute, Hamilton, Ontario

Dr. Jihong Chen is a gastroenterologist and an Associate Professor of Medicine at McMaster University. Her clinic focuses on evidence-based, non-invasive diagnosis and treatment of human gastrointestinal dysmotility and the clinical application of hydrogen/methane breath tests. Her research is focused on neurogenic and myogenic control of gastrointestinal motility, high-resolution colonic and anorectal manometry, autonomic function assessment, non-invasive neuromodulation for refractory gastrointestinal motility disorders, and pathophysiology of intestinal bacterial overgrowth.

Jan D. Huizinga, PhD, McMaster University, Department of Medicine, Division of Gastroenterology; Farncombe Family Digestive Health Research Institute; School of Biomedical Engineering, Hamilton, Ontario

Dr. Jan Huizinga is a Professor of Medicine at McMaster University. His research interest is in elucidating the control mechanism of gastrointestinal motility. He is an expert on intestinal pacemaker cells, the interstitial cells of Cajal (ICC). Currently, his research is focusing on clinical studies with an emphasis on the role of the extrinsic autonomic nervous system and ICC in dysmotilities of the gastrointestinal tract.

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Published

2023-12-13

How to Cite

1.
Chen J, Huizinga JD. Hydrogen and methane breath testing for abdominal bloating of small intestinal origin. Can Allergy Immunol Today [Internet]. 2023 Dec. 13 [cited 2024 Oct. 18];3(3):17–25. Available from: https://canadianallergyandimmunologytoday.com/article/view/3-3-chen_huizinga

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