Treatment and Management of Chronic Cough in Children
DOI:
https://doi.org/10.58931/cait.2024.4373Abstract
Chronic cough (CC) in children is common and most often post-viral in nature. CC in children should be comprehensively evaluated and the underlying etiology treated to prevent irreversible lung damage. Refractory chronic cough (RCC) is proposed as a distinct clinical entity in children, which is defined by a persistent cough that does not resolve after comprehensive evaluation and adherence to systematic, guideline-based treatments. RCC may involve a heightened cough reflex sensitivity or altered neural regulation influenced by genetic, environmental, or immunologic factors. This review focuses on the definition, diagnostic approach, and evidence-based management of pediatric RCC, emphasizing the need for a multidisciplinary approach and highlighting research gaps for future targeted therapies.
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