Pearls from the 2024 European Respiratory Congress

Authors

  • Manali Mukherjee, MD Division of Respirology, McMaster University (primary), Hamilton, ON, The Research Institute, St. Joseph’s Healthcare, Hamilton, ON, McMaster Immunology Research Center, McMaster University, Hamilton, ON, Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON

DOI:

https://doi.org/10.58931/cait.2024.4374

Abstract

The European Respiratory Congress 2024, held from September 7th to 11th, 2024, in Vienna, Austria, featured several presentations on airway diseases, interstitial lung diseases, bronchiectasis, and critical care, with a focus on emerging therapies, particularly on asthma and chronic obstructive pulmonary disease (COPD).

Author Biography

Manali Mukherjee, MD, Division of Respirology, McMaster University (primary), Hamilton, ON, The Research Institute, St. Joseph’s Healthcare, Hamilton, ON, McMaster Immunology Research Center, McMaster University, Hamilton, ON, Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON

Dr. Mukherjee is an Assistant Professor in the Division of Respirology, Department of Medicine, and a translational scientist affiliated with the Research Institute of St. Joe's, Hamilton. She has demonstrated expertise in investigating inflammatory mechanisms of chronic respiratory diseases, in particular autoimmunity, response to treatment and development/validation of clinical biomarkers. Her research has identified the presence of localized autoimmune responses in the airways of patients with complex airways disease and determined their pathogenic role in driving disease severity.
Recently, she has identified autoimmune responses in acute-severe COVID and linked autoimmunity with post-acute COVID-19 sequelae (or Long COVID). In the field of respiratory medicine, she published ~65 manuscripts, and in the past 5 years these have accumulated >2500 citations (Google Scholar h-index 24, i10-index 40). Dr. Mukherjee’s research program focuses on “Lung autoimmunity and biomarkers”. She is the past recipient of the Emerging Researcher Award in Allergic Asthma awarded conjointly by the Canadian Institutes of Health Research (CIHR) and the Canadian Asthma, Allergy and Immunology Foundation (CAAIF). Her lab is funded by federal and non-federal sources including CIHR-ICRH and industry. Dr. Mukherjee was recently named the AstraZeneca Chair in Respiratory Diseases (2023-2028).

References

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Bhalla A, Zhao N, Rivas DD, Ho T, Perez de Llano L, Mukherjee M, et al. Exacerbations of severe asthma while on anti-IL-5 biologics. J Investig Allergol Clin Immunol. 2020;30(5):307-316. doi:10.18176/jiaci.0628

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Mukherjee M, Huang C, Venegas-Garrido C, Zhang K, Bhalla A, Ju X, et al. Benralizumab normalizes sputum eosinophilia in severe asthma uncontrolled by Anti-IL-5 antibodies: a single-blind, placebo-controlled clinical trial. Am J Respir Crit Care Med. 2023;208(12):1330-1335. doi:10.1164/rccm.202308-1413LE

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Salter B, Lacy P, Mukherjee M. Biologics in asthma: a molecular perspective to precision medicine. Front Pharmacol. 2021;12:793409. doi:10.3389/fphar.2021.793409

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Published

2024-12-19

How to Cite

1.
Mukherjee M. Pearls from the 2024 European Respiratory Congress. Can Allergy Immunol Today [Internet]. 2024 Dec. 19 [cited 2024 Dec. 21];4(3):24–28. Available from: https://canadianallergyandimmunologytoday.com/article/view/4-3-Mukherjee

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